Anti-wrinkle and muscle relaxation program

 

This is one of the most popular aesthetic procedures used to achieve a slimmer facial contour, reduce wrinkles, minimize excessive sweating, and eliminate body odor. It has become highly popular in Thailand. Although the results are not permanent, the changes are real, noticeable, and appear relatively quickly. This has led many people to choose this treatment as a way to enhance their facial shape and restore a youthful appearance. In the beauty industry, this procedure is commonly referred to as “Bo injection”

What is Facial Contouring with Wrinkle-Relaxing and Muscle-Relaxing Agents?

It is a purified protein that works on the nervous system. It blocks neurotransmitters that send signals to the muscles in the treated area, resulting in muscle relaxation and reduced muscle contraction.

In the past, wrinkle- and muscle-relaxing substances were used medically to treat conditions such as urinary incontinence, muscle spasms, severe headaches, and eye disorders like strabismus.

In the field of aesthetics, the muscle-relaxing benefits of it have been widely applied to reduce wrinkles. When injected into small facial muscles, wrinkles on the face relax, muscle size is reduced, and the face appears more contoured and smoother. Importantly, this treatment does not damage the muscles and normal sensation remains intact.

How Do Wrinkle-Relaxing and Muscle-Relaxing Agents Work?

Once injected, they act as a neurotoxin, affecting the nervous system. This temporarily reduces the activity of the targeted muscles, limiting their movement. As a result, they help diminish wrinkles, slim the jawline, contour the face, and improve skin firmness.

Because of these benefits, is widely used to reduce expression lines on areas such as the forehead, between the eyebrows, and around the eyes (crow’s feet). It is also used to reduce the size of jaw muscles for a slimmer face shape, lift and define the facial contour, and create a more youthful, firm appearance.

In addition to aesthetic uses, botulinum toxin injections are also effective for reducing excessive sweating in areas such as the underarms, palms, and soles of the feet.

Results of Wrinkle-Relaxing and Muscle-Relaxing Injections

The time it takes to see results varies depending on the injection site, the brand, the size of the muscle, and the amount of Botulinum Toxin used. The approximate time to see results in each area is as follows:

  • Jawline: About 4-6 weeks
  • Wrinkles: About 2 weeks
  • Face lift: About 2-4 weeks

After injections, the effects typically last around 4-8 months, depending on various factors such as the injection site, the brand of Botulinum Toxin, and post-injection care.

Injection Areas and Benefits of Wrinkle-Relaxing and Muscle-Relaxing Agents

  • Jawline: Helps relax and weaken the jaw muscles, reducing their size and making the face appear slimmer. Suitable for individuals with large jaw muscles, but not recommended for those with sunken cheeks and significant facial sagging.
  • Face Lift: Helps tighten the skin around the jawline, creating a more defined jawbone and well-contoured face. It can also make the face appear slimmer. Suitable for patients without significant sagging issues.
  • Underarms or Sweat Reduction: Helps reduce the activity of sweat glands, leading to less sweating, especially in the underarm area. As sweating decreases, body odor also reduces.
  • Nose Wings: Helps narrow the appearance of wide nasal wings, making the nostrils look smaller.
  • Wrinkles: Helps reduce wrinkles that appear with facial expressions on the forehead, between the eyebrows, around the eyes, and on the nose. This leads to smoother, tighter skin, a more youthful appearance, and can prevent permanent wrinkles on the face.
  • Calf Reduction: Helps slim down the calf muscles, allowing for a more confident display of slender legs.
  • Pores: Helps tighten large pores and reduces facial oiliness.

How Many Brands of Wrinkle-Relaxing and Muscle-Relaxing Agents Are There?

Currently, wrinkle-relaxing and muscle-relaxing injections come in various brands from different countries, all certified by the Thai FDA. Each brand has its own unique production process, resulting in distinct characteristics and benefits.

At Pruksa Clinic, we offer four trusted brands as follows

Dysport (UK)

Dysport is a brand from the United Kingdom, with its own unique unit measurement.

Key strengths:

  • The medication disperses more widely, rather than concentrating in a narrow area

  • Excellent for facial lifting and contouring, providing a natural and firm look

  • Effective for reducing excessive sweating

  • Suitable for treating larger muscle groups such as the upper arms and calves

  • Because of its wider spread, results are often more noticeable and well-defined

Allergan (USA)

Allergan is the first brand approved by the US FDA. It is highly purified—up to 99.5% purity—which minimizes the risk of resistance.

Key strengths:

  • Provides precise and consistent results

  • Offers the longest-lasting effect among brands

  • Ideal for treating various facial wrinkles

  • Effective for jaw reduction and facial contouring for a slimmer V-shaped face

Nabo (Korea)

Nabo is a brand from South Korea, approved by the US FDA, with a purity level of 98.7%.

Key strengths:

  • One of the fastest-acting Korean brands, delivering results more quickly than most other Korean brand

  • Helps with facial contouring, jaw slimming, and wrinkle reduction

  • Creates a natural, youthful appearance without stiffness

  • Especially suitable for those who need quick results (e.g., for events or special occasions)

Xeomin (Germany)

Xeomin is a brand from Germany that temporarily reduces muscle activity, making the muscles smaller and helping to smooth out wrinkles.

Key strengths:

  • Especially suitable for patients who have developed resistance to other botulinum toxins

  • Commonly used to treat wrinkles across the face, such as the forehead, frown lines, crow’s feet, and fine lines under the eyes

  • Helps with facial contouring, including reducing cheekbone prominence and slimming the jawline

  • Highly purified formula, without unnecessary complexing proteins

  • The medication does not cluster too narrowly, allowing for a natural look after treatment — the face does not appear overly tight or stiff

Preparation Before Wrinkle-Relaxing and Muscle-Relaxing Injections

  • Choose a reputable clinic and an experienced doctor.
  • Always verify the Botulinum Toxin product before injection to ensure it is genuine and meets FDA standards. Check that the information on the box and vial match or use the QR code some brands provide to verify the product.
  • Avoid alcohol for 24 hours before the injection.
  • If you are taking blood-thinning medication, consult with your doctor beforehand.
  • Avoid vitamins that can make blood clotting difficult, such as Vitamin E, fish oil, ginseng extract, and ginkgo biloba.
  • If you have any chronic medical conditions, inform your doctor before receiving Botulinum Toxin injections.

Post-Treatment Care After Wrinkle-Relaxing and Muscle-Relaxing Injections

  • After the injection, immediately move and contract the injected muscles 1-2 times.
  • Avoid lying down for 3 hours.
  • Avoid all forms of heat and activities that cause facial flushing for about 2 weeks.
  • Refrain from consuming alcohol, eating barbeque, grilling, shabu-shabu, or any food that requires sitting near a hot stove.
  • Avoid facial treatments and massages for 2 weeks after the injection.

Is (Wrinkle-Relaxing and Muscle-Relaxing Injections) Safe?

At Pruksa Clinic, we use only leading global brands such as Allergan, Dysport, Nabota, and Xeomin. All of these products are FDA-approved by trusted authorities, including the Thai FDA, US FDA, and Korean FDA.

This ensures that the botulinum toxin used is safe, effective, and of high quality. It can be injected into the face or body, and the substance will gradually dissolve without leaving any residue in the body.

Importantly, safety also depends on the experience and expertise of the injecting physician. At Pruksa Clinic, treatments are performed by trained professionals, ensuring natural results and patient safety.

How Often Should Wrinkle-Relaxing and Muscle-Relaxing Injections Be Done?

In general, it is recommended to wait at least 4–6 months between treatments. Injections should not be done too frequently, as this may increase the risk of the body developing resistance to the toxin, which can reduce its effectiveness over time.

With proper intervals, patients can maintain safe, natural, and long-lasting results.