{"id":10706,"date":"2025-07-29T08:07:59","date_gmt":"2025-07-29T08:07:59","guid":{"rendered":"https:\/\/www.pruksaclinic.com\/?p=10706"},"modified":"2025-08-11T07:19:46","modified_gmt":"2025-08-11T07:19:46","slug":"%e4%b8%8d%e8%bf%90%e5%8a%a8%e4%b9%9f%e8%83%bd%e5%87%8f%e8%82%a5%ef%bc%8c%e6%98%af%e7%9c%9f%e7%9a%84%e5%90%97%ef%bc%9f%e7%ad%94%e6%a1%88%e9%83%bd%e5%9c%a8%e8%bf%99%e9%87%8c%ef%bc%81","status":"publish","type":"post","link":"https:\/\/www.pruksaclinic.com\/zh-hant\/%e4%b8%8d%e8%bf%90%e5%8a%a8%e4%b9%9f%e8%83%bd%e5%87%8f%e8%82%a5%ef%bc%8c%e6%98%af%e7%9c%9f%e7%9a%84%e5%90%97%ef%bc%9f%e7%ad%94%e6%a1%88%e9%83%bd%e5%9c%a8%e8%bf%99%e9%87%8c%ef%bc%81\/","title":{"rendered":"\u4e0d\u8fd0\u52a8\u4e5f\u80fd\u51cf\u80a5\uff0c\u662f\u771f\u7684\u5417\uff1f\u7b54\u6848\u90fd\u5728\u8fd9\u91cc\uff01"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-flat ez-toc-counter ez-toc-transparent ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<span class=\"ez-toc-title-toggle\"><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.pruksaclinic.com\/zh-hant\/%e4%b8%8d%e8%bf%90%e5%8a%a8%e4%b9%9f%e8%83%bd%e5%87%8f%e8%82%a5%ef%bc%8c%e6%98%af%e7%9c%9f%e7%9a%84%e5%90%97%ef%bc%9f%e7%ad%94%e6%a1%88%e9%83%bd%e5%9c%a8%e8%bf%99%e9%87%8c%ef%bc%81\/#%E4%B8%8D%E8%BF%90%E5%8A%A8%E4%B9%9F%E8%83%BD%E5%87%8F%E8%82%A5%EF%BC%8C%E6%98%AF%E7%9C%9F%E7%9A%84%E5%90%97%EF%BC%9F%E7%AD%94%E6%A1%88%E9%83%BD%E5%9C%A8%E8%BF%99%E9%87%8C%EF%BC%81\" >\u4e0d\u8fd0\u52a8\u4e5f\u80fd\u51cf\u80a5\uff0c\u662f\u771f\u7684\u5417\uff1f\u7b54\u6848\u90fd\u5728\u8fd9\u91cc\uff01<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.pruksaclinic.com\/zh-hant\/%e4%b8%8d%e8%bf%90%e5%8a%a8%e4%b9%9f%e8%83%bd%e5%87%8f%e8%82%a5%ef%bc%8c%e6%98%af%e7%9c%9f%e7%9a%84%e5%90%97%ef%bc%9f%e7%ad%94%e6%a1%88%e9%83%bd%e5%9c%a8%e8%bf%99%e9%87%8c%ef%bc%81\/#1_Saxenda%EF%BC%88%E5%88%A9%E6%8B%89%E9%B2%81%E8%82%BD_Liraglutide%EF%BC%89\" >1. Saxenda\uff08\u5229\u62c9\u9c81\u80bd Liraglutide\uff09<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.pruksaclinic.com\/zh-hant\/%e4%b8%8d%e8%bf%90%e5%8a%a8%e4%b9%9f%e8%83%bd%e5%87%8f%e8%82%a5%ef%bc%8c%e6%98%af%e7%9c%9f%e7%9a%84%e5%90%97%ef%bc%9f%e7%ad%94%e6%a1%88%e9%83%bd%e5%9c%a8%e8%bf%99%e9%87%8c%ef%bc%81\/#2_Wegovy%EF%BC%88%E5%8F%B8%E7%BE%8E%E6%A0%BC%E9%B2%81%E8%82%BD_Semaglutide%EF%BC%89\" >2. Wegovy\uff08\u53f8\u7f8e\u683c\u9c81\u80bd Semaglutide\uff09<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.pruksaclinic.com\/zh-hant\/%e4%b8%8d%e8%bf%90%e5%8a%a8%e4%b9%9f%e8%83%bd%e5%87%8f%e8%82%a5%ef%bc%8c%e6%98%af%e7%9c%9f%e7%9a%84%e5%90%97%ef%bc%9f%e7%ad%94%e6%a1%88%e9%83%bd%e5%9c%a8%e8%bf%99%e9%87%8c%ef%bc%81\/#Mounjaro%EF%BC%88Tirzepatide%EF%BC%89\" >Mounjaro\uff08Tirzepatide\uff09<\/a><\/li><li class='ez-toc-page-1'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.pruksaclinic.com\/zh-hant\/%e4%b8%8d%e8%bf%90%e5%8a%a8%e4%b9%9f%e8%83%bd%e5%87%8f%e8%82%a5%ef%bc%8c%e6%98%af%e7%9c%9f%e7%9a%84%e5%90%97%ef%bc%9f%e7%ad%94%e6%a1%88%e9%83%bd%e5%9c%a8%e8%bf%99%e9%87%8c%ef%bc%81\/#%E5%A5%BD%E5%B8%AE%E6%89%8B%EF%BC%8C%E4%BD%86%E4%BB%8D%E9%9C%80%E8%87%AA%E5%BE%8B\" >\u597d\u5e2e\u624b\uff0c\u4f46\u4ecd\u9700\u81ea\u5f8b<\/a><\/li><\/ul><\/nav><\/div>\n<h1><span class=\"ez-toc-section\" id=\"%E4%B8%8D%E8%BF%90%E5%8A%A8%E4%B9%9F%E8%83%BD%E5%87%8F%E8%82%A5%EF%BC%8C%E6%98%AF%E7%9C%9F%E7%9A%84%E5%90%97%EF%BC%9F%E7%AD%94%E6%A1%88%E9%83%BD%E5%9C%A8%E8%BF%99%E9%87%8C%EF%BC%81\"><\/span><strong>\u4e0d\u8fd0\u52a8\u4e5f\u80fd\u51cf\u80a5\uff0c\u662f\u771f\u7684\u5417\uff1f\u7b54\u6848\u90fd\u5728\u8fd9\u91cc\uff01<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>\u5bf9\u5f88\u591a\u4eba\u6765\u8bf4\uff0c\u63d0\u5230\u51cf\u80a5\uff0c\u5f80\u5f80\u5c31\u4f1a\u8054\u60f3\u5230\u201c\u8fd0\u52a8\u201d\u8fd9\u4e24\u4e2a\u5b57\u3002\u4f46\u73b0\u5b9e\u751f\u6d3b\u4e2d\uff0c\u5e76\u4e0d\u662f\u6bcf\u4e2a\u4eba\u6bcf\u5929\u90fd\u6709\u65f6\u95f4\u53bb\u5065\u8eab\u623f\uff0c\u6216\u662f\u4e0b\u73ed\u540e\u8fd8\u6709\u7cbe\u529b\u5168\u529b\u953b\u70bc\u8eab\u4f53\u3002\u90a3\u4e48\u2026\u2026\u6211\u4eec\u771f\u7684\u53ef\u4ee5\u5728\u5b8c\u5168\u4e0d\u8fd0\u52a8\u7684\u60c5\u51b5\u4e0b\u51cf\u80a5\u5417\uff1f<\/p>\n<p>\u7b54\u6848\u662f\u2026\u2026\u53ef\u4ee5\u505a\u5230\uff01\u4f46\u53ef\u80fd\u5e76\u4e0d\u5bb9\u6613\uff0c\u800c\u4e14\u9700\u8981\u7528\u67d0\u4e9b\u81ea\u5f8b\u884c\u4e3a\u6765\u66ff\u4ee3\uff0c\u4f8b\u5982\u63a7\u5236\u996e\u98df\u3001\u7ba1\u7406\u538b\u529b\uff0c\u4ee5\u53ca\u4fdd\u8bc1\u5145\u8db3\u7761\u7720\u3002\u8fd9\u4e9b\u56e0\u7d20\u5bf9\u4f53\u5185\u6fc0\u7d20\u3001\u9965\u997f\u611f\u4ee5\u53ca\u8102\u80aa\u50a8\u5b58\u7684\u5f71\u54cd\uff0c\u8fdc\u8fdc\u8d85\u8fc7\u8bb8\u591a\u4eba\u7684\u60f3\u8c61\u3002<\/p>\n<ol>\n<li><strong>\u63a7\u5236\u996e\u98df\uff0c\u800c\u4e0d\u662f<\/strong><strong>\u201c<\/strong><strong>\u8282\u98df<\/strong><strong>\u201d<\/strong><br \/>\n\u4e0e\u5176\u8ba9\u81ea\u5df1\u997f\u5230\u53d7\u4e0d\u4e86\uff0c\u4e0d\u5982\u9010\u6b65\u8c03\u6574\u996e\u98df\u4e60\u60ef\uff0c\u4f8b\u5982\u51cf\u5c11\u7cbe\u5236\u78b3\u6c34\u3001\u5c11\u5403\u751c\u98df\u3001\u591a\u559d\u6c34\u3001\u5403\u5f97\u6162\u4e00\u70b9\u3002\u8fd9\u4e9b\u884c\u4e3a\u80fd\u8ba9\u8eab\u4f53\u66f4\u5feb\u611f\u5230\u9971\u8db3\uff0c\u800c\u65e0\u9700\u5403\u592a\u591a\u3002<\/li>\n<li><strong>\u597d\u597d\u7761\u89c9\uff0c\u4f53\u91cd\u81ea\u7136\u4e0b\u964d<\/strong><br \/>\n\u591a\u9879\u7814\u7a76\u53d1\u73b0\uff0c\u7761\u7720\u4e0d\u8db3\u7684\u4eba\u66f4\u5bb9\u6613\u5728\u767d\u5929\u4e71\u5403\u4e1c\u897f\uff0c\u800c\u4e14\u65b0\u9648\u4ee3\u8c22\u6548\u7387\u4e5f\u4f1a\u4e0b\u964d\u3002\u4fdd\u6301\u5145\u8db3\u7761\u7720\uff08\u6bcf\u665a\u81f3\u5c117\u20138\u5c0f\u65f6\uff09\u662f\u63a7\u5236\u4f53\u91cd\u7684\u5173\u952e\u56e0\u7d20\u4e4b\u4e00\u3002<\/li>\n<li><strong>\u51cf\u5c11\u538b\u529b\uff0c\u4f53\u91cd\u4e5f\u4f1a\u51cf\u8f7b<\/strong><br \/>\n\u538b\u529b\u4f1a\u4fc3\u4f7f\u8eab\u4f53\u5206\u6ccc\u76ae\u8d28\u9187\uff08Cortisol\uff09\uff0c\u8ba9\u4eba\u66f4\u60f3\u5403\u751c\u98df\u548c\u9ad8\u8102\u80aa\u98df\u7269\u3002\u900f\u8fc7\u7ba1\u7406\u538b\u529b\uff0c\u4f8b\u5982\u51a5\u60f3\u3001\u8f7b\u677e\u6563\u6b65\u3001\u51cf\u5c11\u5c4f\u5e55\u65f6\u95f4\u7b49\u65b9\u5f0f\uff0c\u53ef\u4ee5\u8ba9\u5fc3\u60c5\u5e73\u9759\uff0c\u8fdb\u800c\u4e0d\u77e5\u4e0d\u89c9\u5730\u5403\u5f97\u66f4\u5c11\u3002<\/li>\n<li><strong>\u8c03\u6574\u8377\u5c14\u8499\u5e73\u8861\uff0c\u8ba9\u51cf\u80a5\u66f4\u8f7b\u677e<\/strong><br \/>\n\u6709\u65f6\u5019\u80a5\u80d6\u5e76\u4e0d\u662f\u56e0\u4e3a\u5403\u592a\u591a\u6216\u7f3a\u4e4f\u8fd0\u52a8\uff0c\u800c\u662f\u56e0\u4e3a\u4f53\u5185\u7684\u65b0\u9648\u4ee3\u8c22\u4e0e\u8377\u5c14\u8499\u51fa\u4e86\u95ee\u9898\uff0c\u4f8b\u5982\u80f0\u5c9b\u7d20\u6297\u6027\u6216\u7626\u4f53\u7d20\uff08Leptin\uff09\u6297\u6027\u3002<\/li>\n<\/ol>\n<p>\u5982\u4eca\u5df2\u6709\u533b\u5b66\u65b9\u6cd5\u53ef\u4ee5\u5e2e\u52a9\u201c\u91cd\u8bbe\u9965\u997f\u611f\u201d\uff0c\u8ba9\u8eab\u4f53\u91cd\u65b0\u638c\u63a7\u81ea\u5df1\uff0c\u4f8b\u5982\u4f7f\u7528 GLP-1 \u7c7b\u836f\u7269\uff0c\u53ef\u4ee5\u5e2e\u52a9\u6211\u4eec\u66f4\u5feb\u4ea7\u751f\u9971\u8db3\u611f\u3001\u51cf\u5c11\u8fdb\u98df\u91cf\uff0c\u5e76\u66f4\u597d\u5730\u63a7\u5236\u8840\u7cd6\u6c34\u5e73\u3002\u867d\u7136\u8fd9\u5e76\u4e0d\u662f\u6377\u5f84\uff0c\u4f46\u5374\u662f\u4e00\u4e2a\u5f88\u597d\u7684\u8f85\u52a9\u5de5\u5177\uff0c\u9002\u5408\u90a3\u4e9b\u4ece\u96f6\u5f00\u59cb\uff0c\u6216\u66fe\u5c1d\u8bd5\u5176\u4ed6\u65b9\u6cd5\u672a\u679c\u7684\u4eba\u3002<\/p>\n<p><em><strong>\u201c\u51cf\u80a5\u4e0d\u4e00\u5b9a\u8981\u4ece\u5065\u8eab\u5f00\u59cb\uff0c\u800c\u662f\u4ece\u4e86\u89e3\u81ea\u5df1\u8eab\u4f53\u5f00\u59cb\u3002\u201d<\/strong><\/em><br \/>\n\u6709\u4e9b\u4eba\u53ef\u80fd\u4ece\u6539\u53d8\u996e\u98df\u5f00\u59cb\uff0c\u6709\u4e9b\u4eba\u4ece\u6539\u5584\u7761\u7720\u5f00\u59cb\uff0c\u4e5f\u6709\u4e9b\u4eba\u9009\u62e9\u5148\u54a8\u8be2\u533b\u751f\uff0c\u4ee5\u627e\u51fa\u6700\u9002\u5408\u81ea\u5df1\u8eab\u4f53\u7684\u51cf\u91cd\u65b9\u6cd5\u3002\u56e0\u4e3a\u6700\u7ec8\u5065\u5eb7\u4e0d\u4ec5\u662f\u5916\u5f62\uff0c\u66f4\u662f\u4eba\u751f\u6bcf\u4e00\u6b65\u7684\u5b89\u5fc3\u4e0e\u81ea\u5728\u3002<\/p>\n<p>\u63a5\u4e0b\u6765\u7684\u6587\u7ae0\uff0c\u6211\u4eec\u5c06\u7ee7\u7eed\u5206\u4eab\u7531\u533b\u751f\u8f85\u52a9\u7684\u51cf\u91cd\u65b9\u6848\uff0c\u5982 Saxenda\u3001Wegovy \u548c Mounjaro\uff0c\u5e76\u4ee5\u8fde\u8d2f\u3001\u6613\u61c2\u3001\u4e2d\u7acb\u7684\u65b9\u5f0f\u4ecb\u7ecd\uff0c\u800c\u4e0d\u6d89\u53ca\u4efb\u4f55\u76f4\u9500\u63a8\u5e7f\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>\u90a3\u4e48\uff0c\u5982\u679c\u60f3\u8ba9\u8eab\u4f53<\/strong><strong>\u201c<\/strong><strong>\u91cd\u65b0\u5f00\u59cb<\/strong><strong>\u201d<\/strong><strong>\u5e76\u501f\u52a9\u4e00\u4e9b\u8f85\u52a9\u5de5\u5177\u8be5\u600e\u4e48\u529e\uff1f<\/strong><\/span><br \/>\n\u5982\u4eca\u5df2\u6709\u533b\u7597\u521b\u65b0\u53ef\u4ee5\u5e2e\u52a9\u51cf\u91cd\u6210\u529f\u7684\u51e0\u7387\u66f4\u9ad8\uff0c\u7279\u522b\u662f\u5bf9\u4e8e\u90a3\u4e9b\u5c1d\u8bd5\u8fc7\u591a\u79cd\u65b9\u6cd5\u4f46\u4ecd\u672a\u89c1\u6548\u7684\u4eba\uff0c\u4f8b\u5982\u5df2\u7ecf\u63a7\u5236\u996e\u98df\u3001\u5c1d\u8bd5\u8fc7\u4e0d\u5403\u665a\u9910\uff0c\u4f46\u4f9d\u7136\u65e0\u6548\uff0c\u6216\u8005\u4e00\u4e9b\u4eba\u5176\u5b9e\u60a3\u6709\u80f0\u5c9b\u7d20\u62b5\u6297\u5374\u5e76\u4e0d\u81ea\u77e5\u3002<\/p>\n<p>GLP-1 \u4ee5\u53ca GIP\/GLP-1 \u7c7b\u836f\u7269\uff0c\u73b0\u5df2\u88ab\u5f00\u53d1\u6210\u201c\u51cf\u91cd\u7b14\u201d\uff08\u6ce8\u5c04\u7b14\uff09\u7684\u5f62\u5f0f\uff0c\u5728\u533b\u751f\u6307\u5bfc\u4e0b\u4f7f\u7528\uff0c\u5e2e\u52a9\u8eab\u4f53\u63a7\u5236\u9965\u997f\u611f\u3001\u5ef6\u957f\u9971\u8179\u65f6\u95f4\u3001\u7a33\u5b9a\u8840\u7cd6\u6c34\u5e73\uff0c\u5e76\u63d0\u5347\u4ee3\u8c22\u6548\u7387\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"1_Saxenda%EF%BC%88%E5%88%A9%E6%8B%89%E9%B2%81%E8%82%BD_Liraglutide%EF%BC%89\"><\/span><strong>1. Saxenda\uff08\u5229\u62c9\u9c81\u80bd Liraglutide<\/strong><strong>\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Saxenda \u662f\u4e00\u79cd\u7528\u4e8e\u51cf\u91cd\u7684\u6ce8\u5c04\u836f\u7269\uff0c\u9002\u7528\u4e8e\u8d85\u91cd\u6216\u80a5\u80d6\u7684\u6210\u4eba\u548c12\u5c81\u4ee5\u4e0a\u7684\u513f\u7ae5\u3002\u5b83\u901a\u8fc7\u6a21\u62df\u4f53\u5185\u81ea\u7136\u6fc0\u7d20 GLP-1 \u7684\u4f5c\u7528\u6765\u6291\u5236\u98df\u6b32\u4e0e\u6444\u98df\u884c\u4e3a\u3002Saxenda \u9700\u914d\u5408\u4f4e\u70ed\u91cf\u996e\u98df\u53ca\u589e\u52a0\u8fd0\u52a8\u6765\u8f85\u52a9\u4f53\u91cd\u63a7\u5236\uff0c\u662f GLP-1 \u836f\u7269\u5bb6\u65cf\u4e2d\u7684\u5148\u9a71\u4e4b\u4e00\uff0c\u80fd\u591f\u5e2e\u52a9\u964d\u4f4e\u98df\u6b32\u3001\u63d0\u5347\u9971\u8179\u611f\uff0c\u9700\u6bcf\u65e5\u6ce8\u5c04\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>1.1 Saxenda \u7684\u4f5c\u7528\u673a<\/strong><strong>\u5236<\/strong><\/span><\/p>\n<p>Saxenda \u7684\u4e3b\u8981\u6d3b\u6027\u6210\u5206\u4e3a\u5229\u62c9\u9c81\u80bd\uff08Liraglutide\uff09\uff0c\u662f\u4e00\u79cd\u7c7b GLP-1 \u6fc0\u7d20\u3002\u5b83\u901a\u8fc7\u5411\u5927\u8111\u53d1\u9001\u4fe1\u53f7\u6765\u589e\u5f3a\u9971\u8179\u611f\uff0c\u4ece\u800c\u5e2e\u52a9\u66f4\u597d\u5730\u63a7\u5236\u8fdb\u98df\u91cf\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>1.2 \u8c01\u53ef\u4ee5\u4f7f\u7528 Saxenda<\/strong><strong>\uff1f<\/strong><\/span><\/p>\n<p>Saxenda \u9002\u7528\u4e8e 12 \u5c81\u4ee5\u4e0a\u6709\u4f53\u91cd\u95ee\u9898\u6216\u60a3\u6709\u80a5\u80d6\u75c7\u7684\u6210\u4eba\u53ca\u513f\u7ae5\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>1.3 \u4f7f\u7528\u65b9<\/strong><strong>\u6cd5<\/strong><\/span><\/p>\n<ul>\n<li>\u6bcf\u65e5\u6ce8\u5c04 1 \u6b21\uff0c\u4efb\u4f55\u65f6\u95f4\u5747\u53ef\uff08\u5efa\u8bae\u6bcf\u5929\u56fa\u5b9a\u65f6\u95f4\u6ce8\u5c04\uff09<\/li>\n<li>\u63a8\u8350\u6ce8\u5c04\u90e8\u4f4d\uff1a\u8179\u90e8\u3001\u81c0\u90e8\u3001\u5927\u81c2\u6216\u5927\u817f<\/li>\n<li>\u4f7f\u7528\u201c\u9010\u6b65\u52a0\u91cf\u6cd5\u201d (Escalation Dose)\uff0c\u4ece6 mg \u8d77\uff0c\u9010\u6b65\u589e\u52a0\u81f3 3.0 mg<\/li>\n<\/ul>\n<p><span style=\"font-size: 120%;\"><strong>1.4 Saxenda <\/strong><strong>\u9002\u5408\u8c01\uff1f<\/strong><\/span><br \/>\n\u9002\u7528\u4e8e\u5e74\u9f84\u5728 18 \u5c81\u53ca\u4ee5\u4e0a\u3001\u6709\u80a5\u80d6\u95ee\u9898\u7684\u4eba\u58eb\uff0c\u5305\u62ec\u4f53\u8d28\u6307\u6570\uff08BMI\uff09\u4e3a 30 \u6216\u66f4\u9ad8\uff08\u80a5\u80d6\u72b6\u6001\uff09\uff0c\u6216\u4f53\u8d28\u6307\u6570\uff08BMI\uff09\u4e3a 27 \u81f3\u5c0f\u4e8e 30\uff08\u8d85\u91cd\u72b6\u6001\uff09\u4e14\u6709\u4e0e\u4f53\u91cd\u76f8\u5173\u7684\u5065\u5eb7\u95ee\u9898\uff08\u5982\u7cd6\u5c3f\u75c5\u3001\u9ad8\u8840\u538b\u3001\u8840\u8102\u5f02\u5e38\uff0c\u6216\u7761\u7720\u65f6\u547c\u5438\u969c\u788d\uff0c\u88ab\u79f0\u4e3a\u201c\u963b\u585e\u6027\u7761\u7720\u547c\u5438\u6682\u505c\u201d\uff09\u7684\u4eba\u58eb\u3002\u4f7f\u7528\u540e\uff0c\u4f53\u91cd\u4f1a\u5728\u524d 3\u20136 \u4e2a\u6708\u9010\u6e10\u51cf\u5c11\u7ea6 5\u201310%\uff08\u89c6\u4e2a\u4f53\u53cd\u5e94\u800c\u5b9a\uff09\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>1.5 \u6ce8\u5c04\u90e8<\/strong><strong>\u4f4d<\/strong><\/span><\/p>\n<p>Saxenda \u5e94\u6ce8\u5c04\u4e8e\u76ae\u4e0b\uff08subcutaneous\uff09\uff0c\u63a8\u8350\u533a\u57df\u6709\uff1a\u8179\u90e8\u3001\u5927\u817f\u6216\u4e0a\u81c2\u3002\u4e0d\u5e94\u6ce8\u5c04\u5165\u8840\u7ba1\u6216\u808c\u8089\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>1.6 \u5176\u4ed6\u6ce8\u610f\u4e8b<\/strong><strong>\u9879<\/strong><\/span><\/p>\n<ul>\n<li>Saxenda \u51cf\u91cd\u7b14\u542b\u6709\u5229\u62c9\u9c81\u80bd\uff0c\u53ef\u6709\u6548\u63a7\u5236\u98df\u6b32\u4e0e\u5ef6\u7f13\u6d88\u5316\uff0c\u6709\u52a9\u4e8e\u957f\u65f6\u95f4\u4fdd\u6301\u9971\u8db3\u611f\uff0c\u4ece\u800c\u8fbe\u5230\u51cf\u91cd\u76ee\u6807\u3002<\/li>\n<li>\u76f8\u8f83\u4e8e\u4f20\u7edf\u51cf\u80a5\u836f\uff0cSaxenda \u7684\u526f\u4f5c\u7528\u8f83\u8f7b\uff0c\u53ef\u80fd\u51fa\u73b0\u8f7b\u5fae\u6076\u5fc3\u6216\u5455\u5410\uff0c\u4f46\u4e0d\u4f1a\u5f71\u54cd\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u3002<\/li>\n<li>Saxenda \u7279\u522b\u9002\u7528\u4e8e\u4f53\u91cd\u76f8\u5173\u75be\u75c5\u60a3\u8005\uff0c\u5c24\u5176\u662f BMI \u226530\uff0c\u6216 BMI \u226527 \u4e14\u4f34\u6709\u75be\u75c5\u5982\u5fc3\u810f\u75c5\u6216\u7cd6\u5c3f\u75c5\u8005\u3002<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"2_Wegovy%EF%BC%88%E5%8F%B8%E7%BE%8E%E6%A0%BC%E9%B2%81%E8%82%BD_Semaglutide%EF%BC%89\"><\/span><strong>2. Wegovy\uff08\u53f8\u7f8e\u683c\u9c81\u80bd Semaglutide<\/strong><strong>\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Wegovy \u662f\u4e00\u79cd\u6ce8\u5c04\u578b\u51cf\u91cd\u836f\u7269\uff0c\u5176\u4e3b\u8981\u6210\u5206\u4e3a\u53f8\u7f8e\u683c\u9c81\u80bd\uff08Semaglutide\uff09\uff0c\u901a\u8fc7\u6a21\u62df GLP-1 \u8377\u5c14\u8499\u7684\u4f5c\u7528\u6765\u63a7\u5236\u98df\u6b32\uff0c\u4f7f\u9971\u8179\u611f\u66f4\u6301\u4e45\u3002\u5b83\u901a\u5e38\u4e0e\u4f4e\u70ed\u91cf\u996e\u98df\u548c\u8fd0\u52a8\u914d\u5408\u4f7f\u7528\uff0c\u4ee5\u5e2e\u52a9\u51cf\u91cd\u5e76\u964d\u4f4e\u4e0e\u8d85\u91cd\u76f8\u5173\u7684\u5065\u5eb7\u98ce\u9669\u3002Wegovy \u662f GLP-1 \u7684\u65b0\u4e00\u4ee3\u836f\u7269\uff0c\u6700\u521d\u7528\u4e8e\u7cd6\u5c3f\u75c5\u6cbb\u7597\uff0c\u5728\u9ad8\u5242\u91cf\u4e0b\u4e5f\u5c55\u73b0\u51fa\u6781\u4f73\u7684\u51cf\u91cd\u6548\u679c\u3002\u6700\u5927\u7684\u4f18\u70b9\u662f\uff1a<strong>\u6bcf\u5468\u4ec5\u9700\u6ce8\u5c04\u4e00\u6b21<\/strong>\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>2.1 Wegovy \u7684\u4f5c\u7528\u673a<\/strong><strong>\u5236<\/strong><\/span><\/p>\n<p>Wegovy \u901a\u8fc7\u6a21\u62df GLP-1 \u8377\u5c14\u8499\u7684\u4f5c\u7528\u6765\u5de5\u4f5c\uff0c\u8be5\u8377\u5c14\u8499\u7531\u4eba\u4f53\u81ea\u7136\u4ea7\u751f\uff0c\u7528\u4e8e\u8c03\u8282\u98df\u6b32\u548c\u8840\u7cd6\u3002\u5f53\u6211\u4eec\u8fdb\u98df\u65f6\uff0cGLP-1 \u4f1a\u5411\u5927\u8111\u4f20\u9012\u201c\u5df2\u9971\u201d\u4fe1\u53f7\u3002Wegovy \u52a0\u5f3a\u8fd9\u79cd\u9971\u8db3\u611f\uff0c\u4f7f\u4eba\u5403\u5f97\u66f4\u5c11\u3002\u540c\u65f6\u5b83\u8fd8\u80fd\u523a\u6fc0\u80f0\u5c9b\u7d20\u5206\u6ccc\uff0c\u5e2e\u52a9\u964d\u4f4e\u8840\u7cd6\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>2.2 \u8c01\u53ef\u4ee5\u4f7f\u7528 Wegovy<\/strong><strong>\uff1f<\/strong><\/span><\/p>\n<p>Wegovy \u83b7\u51c6\u7528\u4e8e\u60a3\u6709\u4f53\u91cd\u95ee\u9898\u6216\u80a5\u80d6\u7684\u6210\u5e74\u4eba\uff0c\u5e76\u4e14\u4f34\u6709\u76f8\u5173\u5065\u5eb7\u95ee\u9898\uff0c\u5982\u9ad8\u8840\u538b\u30012\u578b\u7cd6\u5c3f\u75c5\u6216\u9ad8\u8840\u8102\u3002\u6b64\u5916\uff0cWegovy \u4e5f\u88ab\u6279\u51c6\u7528\u4e8e\u5e74\u9f84\u572812\u5c81\u4ee5\u4e0a\u7684\u80a5\u80d6\u513f\u7ae5\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>2.3 \u4f7f\u7528\u65b9<\/strong><strong>\u6cd5<\/strong><\/span><\/p>\n<p>\u521d\u671f\u9700\u6309\u6cbb\u7597\u8ba1\u5212\u9010\u6b65\u52a0\u91cf\uff0c\u4ee5\u5e2e\u52a9\u8eab\u4f53\u9002\u5e94\u5e76\u51cf\u5c11\u526f\u4f5c\u7528\u3002\u901a\u5e38\u5982\u4e0b\uff1a<\/p>\n<ul>\n<li>\u7b2c1\u20134\u5468\uff1a\u6bcf\u5468\u6ce8\u5c0425 mg<\/li>\n<li>\u4e4b\u540e\u9010\u6b65\u9012\u589e\u4e3a5 mg\u30011 mg\uff0c\u751a\u81f3\u66f4\u9ad8\uff0c\u89c6\u4e2a\u4f53\u60c5\u51b5\u800c\u5b9a<br \/>\n\u6574\u4e2a\u8fc7\u7a0b\u9700\u5728\u533b\u751f\u76d1\u7763\u4e0b\u8fdb\u884c\uff0c\u4fbf\u4e8e\u8bc4\u4f30\u6548\u679c\u5e76\u4e2a\u6027\u5316\u8c03\u6574\u5242\u91cf\u3002<\/li>\n<\/ul>\n<p><span style=\"font-size: 120%;\"><strong>2.4 Wegovy \u9002\u5408\u54ea\u4e9b\u4eba<\/strong><strong>\uff1f<\/strong><\/span><\/p>\n<p>\u9002\u5408\u5e0c\u671b\u51cf\u91cd <strong>\u8d85\u8fc7<\/strong><strong>10%<\/strong> \u4e14\u4e0d\u5e0c\u671b\u6bcf\u5929\u6ce8\u5c04\u836f\u7269\u7684\u4eba\u7fa4\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>2.5 \u6ce8\u5c04\u90e8<\/strong><strong>\u4f4d<\/strong><\/span><\/p>\n<p>\u53ef\u6ce8\u5c04\u4e8e\u76ae\u4e0b\u4ee5\u4e0b\u4e09\u4e2a\u90e8\u4f4d\uff1a\uff08\u8179\u90e8\uff08\u8ddd\u79bb\u809a\u8110\u81f3\u5c115\u516c\u5206\uff09\uff0c\u4e0a\u81c2\u6216\u5927\u817f\u4e0a\u90e8\u3002\u6bcf\u5468\u53ef\u5728\u540c\u4e00\u90e8\u4f4d\u6ce8\u5c04\uff0c\u4f46\u5efa\u8bae\u6bcf\u6b21\u66f4\u6362\u5177\u4f53\u4f4d\u7f6e\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>2.6 \u5176\u4ed6\u6ce8\u610f\u4e8b<\/strong><strong>\u9879<\/strong><\/span><\/p>\n<ul>\n<li>Wegovy \u662f\u5904\u65b9\u836f\uff0c\u9700\u533b\u751f\u5f00\u7acb\uff0c\u8bf7\u5728\u4f7f\u7528\u524d\u54a8\u8be2\u4e13\u4e1a\u533b\u751f\u3002<\/li>\n<li>\u9700\u914d\u5408\u996e\u98df\u63a7\u5236\u4e0e\u89c4\u5f8b\u8fd0\u52a8\u4ee5\u8fbe\u6700\u4f73\u6548\u679c\u3002<\/li>\n<li>\u53ef\u80fd\u7684\u526f\u4f5c\u7528\u5305\u62ec\uff1a\u6076\u5fc3\u3001\u5455\u5410\u3001\u8179\u6cfb\u6216\u4fbf\u79d8\u3002<\/li>\n<li>\u5b83\u5e76\u975e\u201c\u795e\u836f\u201d\uff0c\u65e0\u6cd5\u7acb\u523b\u53d8\u7626\uff0c\u9700\u957f\u671f\u89c4\u5f8b\u4f7f\u7528\u65b9\u89c1\u6210\u6548\u3002<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ol start=\"3\">\n<li>\n<h2><span class=\"ez-toc-section\" id=\"Mounjaro%EF%BC%88Tirzepatide%EF%BC%89\"><\/span><strong> Mounjaro<\/strong><strong>\uff08<\/strong><strong>Tirzepatide<\/strong><strong>\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Mounjaro\uff08Tirzepatide\uff09\u662f\u4e00\u79cd\u7528\u4e8e\u63a7\u5236\u4f53\u91cd\u548c\u51cf\u91cd\u7684\u836f\u7269\uff0c\u5448\u6ce8\u5c04\u7b14\u5f62\u5f0f\uff0c\u5185\u542b\u4e3b\u8981\u6210\u5206\u4e3a Tirzepatide\uff0c\u662f\u4e00\u79cd\u53cc\u91cd\u6fc0\u52a8\u5242\uff08Dual agonist\uff09\uff0c\u53ef\u540c\u65f6\u523a\u6fc0 GIP \u548c GLP-1\uff0c\u5177\u6709\u63a7\u5236\u98df\u6b32\u3001\u523a\u6fc0\u80f0\u5c9b\u7d20\u5206\u6ccc\u3001\u5ef6\u7f13\u98df\u7269\u6d88\u5316\u3001\u523a\u6fc0\u5927\u8111\u4ea7\u751f\u9971\u8179\u611f\u7b49\u4f5c\u7528\uff0c\u4ece\u800c\u5e2e\u52a9\u51cf\u91cd\uff0c\u540c\u65f6\u8fd8\u80fd\u4fc3\u8fdb\u5fc3\u8840\u7ba1\u5065\u5eb7\u3002\u7531\u4e8e\u8fd9\u4e9b\u7279\u6027\uff0c\u5b83\u5e38\u88ab\u6635\u79f0\u4e3a\u201c\u63a7\u9965\u7b14\u201d\u3002<\/li>\n<\/ol>\n<p><span style=\"font-size: 120%;\"><strong>3.1 Mounjaro \u5982\u4f55\u53d1\u6325\u4f5c\u7528\uff1f<\/strong><\/span><br \/>\nMounjaro \u7684\u4f5c\u7528\u673a\u5236\u662f\u6a21\u62df\u4f53\u5185\u4e24\u79cd\u5929\u7136\u6fc0\u7d20\uff1aGIP\uff08\u8461\u8404\u7cd6\u4f9d\u8d56\u6027\u80f0\u5c9b\u7d20\u4fc3\u6ccc\u591a\u80bd\uff09\u548c GLP-1\uff08\u80f0\u9ad8\u8840\u7cd6\u7d20\u6837\u80bd-1\uff09\u3002\u8be5\u836f\u7269\u80fd\u523a\u6fc0\u80f0\u5c9b\u7d20\u5206\u6ccc\u3001\u964d\u4f4e\u8840\u7cd6\u3001\u5ef6\u7f13\u98df\u7269\u6d88\u5316\uff0c\u5e76\u51cf\u5c11\u98df\u6b32\uff0c\u4ece\u800c\u5e2e\u52a9\u60a3\u8005\u63a7\u5236\u8840\u7cd6\u6c34\u5e73\u5e76\u51cf\u91cd\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>3.2 \u8c01\u53ef\u4ee5\u4f7f\u7528 Mounjaro\uff1f<\/strong><\/span><br \/>\n\u9002\u7528\u4e8e 2 \u578b\u7cd6\u5c3f\u75c5\u7684\u6210\u5e74\u4eba\uff0c\u4ec5\u9760\u996e\u98df\u548c\u8fd0\u52a8\u63a7\u5236\u8840\u7cd6\u6548\u679c\u4e0d\u4f73\u8005\uff0c\u6216\u8d85\u91cd\u6216\u80a5\u80d6\u8005\u3002\u6b64\u5916\uff0cMounjaro \u4e5f\u6b63\u5728\u88ab\u7814\u7a76\u7528\u4e8e\u6709\u80a5\u80d6\u6216\u8d85\u91cd\u95ee\u9898\u7684\u4eba\u7fa4\u7684\u51cf\u91cd\u6cbb\u7597\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>3.3 Mounjaro \u5982\u4f55\u4f7f\u7528<\/strong><\/span><br \/>\nMounjaro\uff08Tirzepatide\uff09\u4f7f\u7528\u521d\u671f\u9700\u8981\u9010\u6b65\u589e\u52a0\u5242\u91cf\u4ee5\u4f7f\u8eab\u4f53\u9002\u5e94\uff0c\u5e76\u51cf\u5c11\u526f\u4f5c\u7528\uff0c\u901a\u5e38\u65b9\u6848\u5982\u4e0b\uff1a<\/p>\n<ul>\n<li>\u7b2c 1\u20134 \u5468\uff1a\u6bcf\u5468 5 mg<\/li>\n<li>\u4e4b\u540e\u9010\u6b65\u589e\u52a0\u4e3a 5 mg\u300110 mg\uff0c\u5e76\u7ee7\u7eed\u589e\u52a0<\/li>\n<\/ul>\n<p>\u6240\u6709\u8fc7\u7a0b\u5e94\u5728\u533b\u751f\u6307\u5bfc\u4e0b\u8fdb\u884c\uff0c\u4ee5\u8bc4\u4f30\u6548\u679c\u5e76\u4e2a\u522b\u8c03\u6574\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>3.4 Mounjaro \u9002\u5408\u8c01<\/strong><\/span><br \/>\n\u9002\u7528\u4e8e\u5e0c\u671b\u63a7\u5236\u8840\u7cd6\u7684 2 \u578b\u7cd6\u5c3f\u75c5\u6210\u5e74\u4eba\uff0c\u4e14\u53ef\u80fd\u5b58\u5728\u8d85\u91cd\u6216\u80a5\u80d6\u95ee\u9898\u7684\u4eba\u7fa4\u3002\u4e5f\u8003\u8651\u7528\u4e8e BMI \u2265 30 \u7684\u6210\u5e74\u4eba\uff0c\u6216 BMI \u2265 27 \u4e14\u4f34\u968f\u4e0e\u4f53\u91cd\u76f8\u5173\u5065\u5eb7\u95ee\u9898\uff08\u5982\u7cd6\u5c3f\u75c5\uff09\u8005\u7684\u51cf\u91cd\u6cbb\u7597\u3002<\/p>\n<p><span style=\"font-size: 120%;\"><strong>3.5 Mounjaro\uff08Tirzepatide\uff09\u53ef\u6ce8\u5c04\u90e8\u4f4d<\/strong><strong>\uff1f<\/strong><\/span><\/p>\n<p><strong>3.5.1 \u8179<\/strong><strong>\u90e8<\/strong><\/p>\n<ul>\n<li>\u6700\u53d7\u6b22\u8fce\u7684\u4f4d\u7f6e\uff0c\u6ce8\u5c04\u65b9\u4fbf\u4e14\u6613\u89c2\u5bdf<\/li>\n<li>\u8ddd\u79bb\u809a\u8110\u81f3\u5c11 2 \u82f1\u5bf8\uff085 \u5398\u7c73\uff09<\/li>\n<li>\u53ef\u56f4\u7ed5\u809a\u8110\u6ce8\u5c04\uff0c\u4f46\u907f\u514d\u6b63\u4e2d\u4f4d\u7f6e<\/li>\n<\/ul>\n<p><strong>3.5.2 \u5927\u817f\u524d<\/strong><strong>\u4fa7<\/strong><\/p>\n<ul>\n<li>\u9002\u5408\u5750\u59ff\u6216\u4ef0\u5367\u817f\u4f38\u76f4\u65f6\u6ce8\u5c04<\/li>\n<li>\u6ce8\u5c04\u4e8e\u5927\u817f\u4e2d\u90e8\uff0c\u4e0d\u5b9c\u8fc7\u4e8e\u9760\u8fd1\u5185\u4fa7\u6216\u5916\u4fa7<\/li>\n<\/ul>\n<p><strong>3.5.3 \u4e0a\u81c2\u540e<\/strong><strong>\u4fa7<\/strong><\/p>\n<ul>\n<li>\u9002\u5408\u6709\u4ed6\u4eba\u534f\u52a9\u65f6\u4f7f\u7528<\/li>\n<li>\u81ea\u884c\u6ce8\u5c04\u8f83\u56f0\u96be\uff0c\u56e0\u4e3a\u89c6\u7ebf\u53d7\u9650<\/li>\n<\/ul>\n<p><span style=\"font-size: 120%;\"><strong>3.6 \u5176\u4ed6\u6ce8\u610f\u4e8b<\/strong><strong>\u9879<\/strong><\/span><\/p>\n<ul>\n<li>Mounjaro \u4e0d\u9002\u7528\u4e8e 1 \u578b\u7cd6\u5c3f\u75c5\u60a3\u8005<\/li>\n<li>\u4f7f\u7528\u524d\u5e94\u54a8\u8be2\u533b\u751f\uff0c\u4ee5\u8bc4\u4f30\u9002\u7528\u6027\u53ca\u53ef\u80fd\u7684\u98ce\u9669<\/li>\n<li>\u6709\u80f0\u817a\u708e\u3001\u80be\u75c5\u3001\u80c3\u6216\u80a0\u9053\u75be\u75c5\u75c5\u53f2\u8005\u53ef\u80fd\u4e0d\u9002\u7528<\/li>\n<li>\u5982\u6709\u8fc7\u654f\u6216\u5176\u4ed6\u5f02\u5e38\u53cd\u5e94\uff0c\u5e94\u544a\u77e5\u533b\u751f<\/li>\n<li>\u5e94\u54a8\u8be2\u533b\u751f\u4e86\u89e3\u53ef\u80fd\u51fa\u73b0\u7684\u526f\u4f5c\u7528\u53ca\u5e94\u5bf9\u65b9\u6cd5<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"%E5%A5%BD%E5%B8%AE%E6%89%8B%EF%BC%8C%E4%BD%86%E4%BB%8D%E9%9C%80%E8%87%AA%E5%BE%8B\"><\/span><strong>\u597d\u5e2e\u624b\uff0c\u4f46\u4ecd\u9700\u81ea\u5f8b<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u5373\u4f7f\u51cf\u91cd\u7b14\u53ef\u4ee5\u8ba9\u63a7\u5236\u98df\u6b32\u53d8\u5f97\u66f4\u5bb9\u6613\uff0c\u4f46\u6301\u4e45\u7684\u6210\u679c\u4f9d\u7136\u53d6\u51b3\u4e8e\u6211\u4eec\u81ea\u8eab\u7684\u884c\u4e3a\uff0c\u65e0\u8bba\u662f\u996e\u98df\u3001\u7761\u7720\u3001\u538b\u529b\u7ba1\u7406\uff0c\u8fd8\u662f\u9009\u62e9\u9002\u5408\u81ea\u5df1\u8eab\u4f53\u7684\u65b9\u6cd5\u3002\u5728 Pruksa\u8bca\u6240\uff0c\u6211\u4eec\u76f8\u4fe1\u8fd9\u662f\u53e6\u4e00\u79cd\u9009\u62e9\uff0c\u4e5f\u662f\u5408\u9002\u7684\u8f85\u52a9\u5de5\u5177\u3002\u5728\u4e13\u4e1a\u533b\u7597\u56e2\u961f\u7684\u6307\u5bfc\u4e0b\uff0c\u662f\u8fc8\u5411<strong>\u957f\u671f\u7231\u81ea\u5df1<\/strong>\u7684\u7b2c\u4e00\u6b65\u3002<\/p>\n\n    <div class=\"xs_social_share_widget xs_share_url after_content \t\tmain_content  wslu-style-1 wslu-share-box-shaped wslu-fill-colored wslu-none wslu-share-horizontal wslu-theme-font-no wslu-main_content\">\n\n\t\t\n        <ul>\n\t\t\t        <\/ul>\n    <\/div> \n","protected":false},"excerpt":{"rendered":"<p>\u4e0d\u8fd0\u52a8\u4e5f\u80fd\u51cf\u80a5\uff0c\u662f\u771f\u7684\u5417\uff1f\u7b54\u6848\u90fd\u5728\u8fd9\u91cc\uff01 \u5bf9\u5f88\u591a\u4eba\u6765\u8bf4\uff0c\u63d0\u5230\u51cf\u80a5\uff0c\u5f80\u5f80\u5c31\u4f1a\u8054\u60f3\u5230\u201c\u8fd0\u52a8\u201d\u8fd9\u4e24\u4e2a\u5b57\u3002\u4f46\u73b0\u5b9e\u751f\u6d3b\u4e2d<\/p>\n","protected":false},"author":1,"featured_media":10324,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[129],"tags":[],"class_list":["post-10706","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category--zh-hant"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ 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